Hydroxychloroquine as antiviral prophylaxis for exposed caregivers to Covid-19: An urgent appraisal is needed.
Identifieur interne : 000D94 ( Main/Exploration ); précédent : 000D93; suivant : 000D95Hydroxychloroquine as antiviral prophylaxis for exposed caregivers to Covid-19: An urgent appraisal is needed.
Auteurs : Rachid Tahiri Joutei Hassani [France] ; Ahmed Bennis [Maroc]Source :
- Journal of infection and public health [ 1876-035X ] ; 2020.
Descripteurs français
- KwdFr :
- Antiviraux (usage thérapeutique), Betacoronavirus (MeSH), Chimioprévention (MeSH), Facteurs âges (MeSH), Humains (MeSH), Hydroxychloroquine (usage thérapeutique), Infections à coronavirus (prévention et contrôle), Pandémies (prévention et contrôle), Personnel de santé (statistiques et données numériques), Pneumopathie virale (prévention et contrôle).
- MESH :
- prévention et contrôle : Infections à coronavirus, Pandémies, Pneumopathie virale.
- statistiques et données numériques : Personnel de santé.
- usage thérapeutique : Antiviraux, Hydroxychloroquine.
- Betacoronavirus, Chimioprévention, Facteurs âges, Humains.
English descriptors
- KwdEn :
- Age Factors (MeSH), Antiviral Agents (therapeutic use), Betacoronavirus (MeSH), Chemoprevention (MeSH), Coronavirus Infections (prevention & control), Health Personnel (statistics & numerical data), Humans (MeSH), Hydroxychloroquine (therapeutic use), Pandemics (prevention & control), Pneumonia, Viral (prevention & control).
- MESH :
- chemical , therapeutic use : Antiviral Agents, Hydroxychloroquine.
- prevention & control : Coronavirus Infections, Pandemics, Pneumonia, Viral.
- statistics & numerical data : Health Personnel.
- Age Factors, Betacoronavirus, Chemoprevention, Humans.
Abstract
BACKGROUND
Since the onset of the new coronavirus pandemic, the world is facing a public health emergency. Repositioning hydroxychloroquine (HQ) seems to be a promising option. Many emerging evidences have converged on the effectiveness of HQ in the treatment of Covid-19 infection. In a recent paper, Gautret et al. suggested that further works are needed to determine if HQ antiviral prophylaxis is useful, especially for healthcare workers.
METHODS
The purpose of this paper is to assess the Covid-19 exposure and risks level among caregivers. For this, we performed research on internet and PubMed by crossing the following keywords: healthcare givers, healthcare workers, doctors, nurses, coronavirus, Covid-19, mortality, infection rate, chloroquine, hydroxychloroquine.
RESULTS
Data on healthcare worker's infection and mortality by Covid-19 are partial and are not systematically published. However, it seems that the infection rate varies between 3.8% and 9% depending on the country. Moreover, the mean age of this population is relatively old, especially in the OECD area.
CONCLUSIONS
Anti-Covid-19 HQ prophylaxis should be urgently accessed, especially for healthcare workers. It is to be hoped that HQ prophylaxis reduces the morbidity and mortality from Covid-19 infection among this population which is particularly exposed and relatively old.
DOI: 10.1016/j.jiph.2020.05.005
PubMed: 32451259
PubMed Central: PMC7211565
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Electronic address: granville-tahiri@levisiologiste.com.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Ambulatory Surgery Department, Avranches Granville Hospital, Granville</wicri:regionArea><wicri:noRegion>Granville</wicri:noRegion><wicri:noRegion>Granville</wicri:noRegion></affiliation></author><author><name sortKey="Bennis, Ahmed" sort="Bennis, Ahmed" uniqKey="Bennis A" first="Ahmed" last="Bennis">Ahmed Bennis</name><affiliation wicri:level="1"><nlm:affiliation>Cardiology Department, Jerada Clinic, Casablanca, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Cardiology Department, Jerada Clinic, Casablanca</wicri:regionArea><wicri:noRegion>Casablanca</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32451259</idno><idno type="pmid">32451259</idno><idno type="doi">10.1016/j.jiph.2020.05.005</idno><idno type="pmc">PMC7211565</idno><idno type="wicri:Area/Main/Corpus">001122</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001122</idno><idno type="wicri:Area/Main/Curation">001122</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">001122</idno><idno type="wicri:Area/Main/Exploration">001122</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Hydroxychloroquine as antiviral prophylaxis for exposed caregivers to Covid-19: An urgent appraisal is needed.</title><author><name sortKey="Tahiri Joutei Hassani, Rachid" sort="Tahiri Joutei Hassani, Rachid" uniqKey="Tahiri Joutei Hassani R" first="Rachid" last="Tahiri Joutei Hassani">Rachid Tahiri Joutei Hassani</name><affiliation wicri:level="1"><nlm:affiliation>Ambulatory Surgery Department, Avranches Granville Hospital, Granville, France. Electronic address: granville-tahiri@levisiologiste.com.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Ambulatory Surgery Department, Avranches Granville Hospital, Granville</wicri:regionArea><wicri:noRegion>Granville</wicri:noRegion><wicri:noRegion>Granville</wicri:noRegion></affiliation></author><author><name sortKey="Bennis, Ahmed" sort="Bennis, Ahmed" uniqKey="Bennis A" first="Ahmed" last="Bennis">Ahmed Bennis</name><affiliation wicri:level="1"><nlm:affiliation>Cardiology Department, Jerada Clinic, Casablanca, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Cardiology Department, Jerada Clinic, Casablanca</wicri:regionArea><wicri:noRegion>Casablanca</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of infection and public health</title><idno type="eISSN">1876-035X</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Age Factors (MeSH)</term><term>Antiviral Agents (therapeutic use)</term><term>Betacoronavirus (MeSH)</term><term>Chemoprevention (MeSH)</term><term>Coronavirus Infections (prevention & control)</term><term>Health Personnel (statistics & numerical data)</term><term>Humans (MeSH)</term><term>Hydroxychloroquine (therapeutic use)</term><term>Pandemics (prevention & control)</term><term>Pneumonia, Viral (prevention & control)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Antiviraux (usage thérapeutique)</term><term>Betacoronavirus (MeSH)</term><term>Chimioprévention (MeSH)</term><term>Facteurs âges (MeSH)</term><term>Humains (MeSH)</term><term>Hydroxychloroquine (usage thérapeutique)</term><term>Infections à coronavirus (prévention et contrôle)</term><term>Pandémies (prévention et contrôle)</term><term>Personnel de santé (statistiques et données numériques)</term><term>Pneumopathie virale (prévention et contrôle)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Coronavirus Infections</term><term>Pandemics</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr"><term>Infections à coronavirus</term><term>Pandémies</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Health Personnel</term></keywords><keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Personnel de santé</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiviraux</term><term>Hydroxychloroquine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Age Factors</term><term>Betacoronavirus</term><term>Chemoprevention</term><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Betacoronavirus</term><term>Chimioprévention</term><term>Facteurs âges</term><term>Humains</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Since the onset of the new coronavirus pandemic, the world is facing a public health emergency. Repositioning hydroxychloroquine (HQ) seems to be a promising option. Many emerging evidences have converged on the effectiveness of HQ in the treatment of Covid-19 infection. In a recent paper, Gautret et al. suggested that further works are needed to determine if HQ antiviral prophylaxis is useful, especially for healthcare workers.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>The purpose of this paper is to assess the Covid-19 exposure and risks level among caregivers. For this, we performed research on internet and PubMed by crossing the following keywords: healthcare givers, healthcare workers, doctors, nurses, coronavirus, Covid-19, mortality, infection rate, chloroquine, hydroxychloroquine.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Data on healthcare worker's infection and mortality by Covid-19 are partial and are not systematically published. However, it seems that the infection rate varies between 3.8% and 9% depending on the country. Moreover, the mean age of this population is relatively old, especially in the OECD area.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>Anti-Covid-19 HQ prophylaxis should be urgently accessed, especially for healthcare workers. It is to be hoped that HQ prophylaxis reduces the morbidity and mortality from Covid-19 infection among this population which is particularly exposed and relatively old.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32451259</PMID><DateCompleted><Year>2020</Year><Month>06</Month><Day>17</Day></DateCompleted><DateRevised><Year>2020</Year><Month>06</Month><Day>30</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1876-035X</ISSN><JournalIssue CitedMedium="Internet"><Volume>13</Volume><Issue>6</Issue><PubDate><Year>2020</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Journal of infection and public health</Title><ISOAbbreviation>J Infect Public Health</ISOAbbreviation></Journal><ArticleTitle>Hydroxychloroquine as antiviral prophylaxis for exposed caregivers to Covid-19: An urgent appraisal is needed.</ArticleTitle><Pagination><MedlinePgn>865-867</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S1876-0341(20)30471-8</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jiph.2020.05.005</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Since the onset of the new coronavirus pandemic, the world is facing a public health emergency. Repositioning hydroxychloroquine (HQ) seems to be a promising option. Many emerging evidences have converged on the effectiveness of HQ in the treatment of Covid-19 infection. In a recent paper, Gautret et al. suggested that further works are needed to determine if HQ antiviral prophylaxis is useful, especially for healthcare workers.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The purpose of this paper is to assess the Covid-19 exposure and risks level among caregivers. For this, we performed research on internet and PubMed by crossing the following keywords: healthcare givers, healthcare workers, doctors, nurses, coronavirus, Covid-19, mortality, infection rate, chloroquine, hydroxychloroquine.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Data on healthcare worker's infection and mortality by Covid-19 are partial and are not systematically published. 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